Turkish Neonatal Society position paper for stem cell therapy in neonates


Cetinkaya M., KOÇ E., Acunas B., AKISU M., ARSAN S., Canpolat F. E., ...More

Global Pediatrics, vol.11, 2025 (Scopus)

  • Publication Type: Article / Article
  • Volume: 11
  • Publication Date: 2025
  • Doi Number: 10.1016/j.gpeds.2024.100239
  • Journal Name: Global Pediatrics
  • Journal Indexes: Scopus
  • Keywords: Neonatal diseases, Neonatology, Position paper, Stem cell therapy
  • Bursa Uludag University Affiliated: Yes

Abstract

Stem cell (SC) therapy has been proposed as a promising therapeutic modality in neonatology, especially for prevention and/or treatment of several interactable diseases such as bronchopulmonary dysplasia, intraventricular hemorrhage, hypoxic-ischemic encephalopathy and others. However, there are several uncertainities in terms of indications, timing, dosage, and safety of SC therapy for routine clinical use in neonates. Herein, a group of Turkish Neonatal Society members evaluated the systematic reviews, meta-analyses, clinical and experimental studies and also case-reports in the literature about the usage of SC therapy in neonatal diseases.