Chromoblastomycosis caused by Fonsecaea pedrosoi: The first molecularly confirmed case from Türkiye

ÇALIŞIR B., YUSUF S., AKSOY M. S., ÖZTÜRK F., BALABAN ADIM Ş., Tüzemen Ü., ...Daha Fazla

Diagnostic Microbiology and Infectious Disease, cilt.116, sa.1, 2026 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 116 Sayı: 1
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1016/j.diagmicrobio.2026.117411
  • Dergi Adı: Diagnostic Microbiology and Infectious Disease
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, Environment Index, MEDLINE
  • Anahtar Kelimeler: Chromoblastomycosis, Fonsecaea pedrosoi, Muriform cells, Türkiye
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

This report describes the first molecularly confirmed case of chromoblastomycosis caused by Fonsecaea pedrosoi in Türkiye. The patient had pruritic, sclerotic, purplish lesions on his right forearm. A biopsy specimen obtained from the lesion was submitted for histopathological examination and microbiological cultivation. Histopathological examination revealed characteristic muriform cells. Culture yielded a dematiaceous fungus, which was identified as F. pedrosoi through internal transcribed spacer (ITS) region sequencing. Itraconazole therapy was administered. After 12-month follow-up, the lesions had regressed significantly. This molecularly confirmed case from a non-endemic country highlights the emerging recognition of F. pedrosoi infections and underscores the importance of clinical awareness for rare fungal pathogens.