Chromoblastomycosis caused by Fonsecaea pedrosoi: The first molecularly confirmed case from Türkiye
Diagnostic Microbiology and Infectious Disease, vol.116, no.1, 2026 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 116 Issue: 1
- Publication Date: 2026
- Doi Number: 10.1016/j.diagmicrobio.2026.117411
- Journal Name: Diagnostic Microbiology and Infectious Disease
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, Environment Index, MEDLINE
- Keywords: Chromoblastomycosis, Fonsecaea pedrosoi, Muriform cells, Türkiye
- Bursa Uludag University Affiliated: Yes
Abstract
This report describes the first molecularly confirmed case of chromoblastomycosis caused by Fonsecaea pedrosoi in Türkiye. The patient had pruritic, sclerotic, purplish lesions on his right forearm. A biopsy specimen obtained from the lesion was submitted for histopathological examination and microbiological cultivation. Histopathological examination revealed characteristic muriform cells. Culture yielded a dematiaceous fungus, which was identified as F. pedrosoi through internal transcribed spacer (ITS) region sequencing. Itraconazole therapy was administered. After 12-month follow-up, the lesions had regressed significantly. This molecularly confirmed case from a non-endemic country highlights the emerging recognition of F. pedrosoi infections and underscores the importance of clinical awareness for rare fungal pathogens.