Atıf İçin Kopyala
Niemsiri V., Wang X., PİRİM D., Radwan Z. H., Bunker C. H., Barmada M. M., ...Daha Fazla
BMC MEDICAL GENETICS, cilt.16, 2015 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
16
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Basım Tarihi:
2015
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Doi Numarası:
10.1186/s12881-015-0250-6
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Dergi Adı:
BMC MEDICAL GENETICS
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Anahtar Kelimeler:
African continental ancestry group, Candidate gene association study, Genetic variation, Haplotypes, Lipids, SCARB1 protein, human, Sequence analysis, DNA, HIGH-DENSITY-LIPOPROTEIN, SCAVENGER RECEPTOR BI, HDL CHOLESTEROL LEVELS, SR-BI, I GENE, TARGETED MUTATION, COMMON VARIANTS, PLASMA-LEVELS, METABOLISM, POLYMORPHISMS
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Bursa Uludağ Üniversitesi Adresli:
Hayır
Özet
Background: High-density lipoprotein cholesterol (HDL-C) exerts many anti-atherogenic properties including its role in reverse cholesterol transport (RCT). Scavenger receptor class B member 1 (SCARB1) plays a key role in RCT by selective uptake of HDL cholesteryl esters. We aimed to explore the genetic contribution of SCARB1 to affecting lipid levels in African Blacks from Nigeria.