In vitro genotoxic effects of the anticancer drug gemcitabine in human lymphocytes

Aydemir N., Celikler S., Bilaloglu R.

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, cilt.582, ss.35-41, 2005 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 582
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1016/j.mrgentox.2004.12.013
  • Dergi Adı: MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.35-41
  • Anahtar Kelimeler: gemcitabine, sister-chromatid exchange, chromosome aberrations, genotoxic, cytotoxic, in vitro, human lymphocytes, DNA-SYNTHESIS, CYTOTOXICITY, MICRONUCLEI
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

This research was carried out to investigate in vitro genotoxic effects of the anticancer agent gemcitabine on the induction of chromosomal aberrations and sister-chromatid exchange in human lymphocytes.