In vitro genotoxic effects of the anticancer drug gemcitabine in human lymphocytes

Aydemir N., Celikler S., Bilaloglu R.

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, vol.582, pp.35-41, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 582
  • Publication Date: 2005
  • Doi Number: 10.1016/j.mrgentox.2004.12.013
  • Journal Name: MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.35-41
  • Keywords: gemcitabine, sister-chromatid exchange, chromosome aberrations, genotoxic, cytotoxic, in vitro, human lymphocytes, DNA-SYNTHESIS, CYTOTOXICITY, MICRONUCLEI
  • Bursa Uludag University Affiliated: Yes

Abstract

This research was carried out to investigate in vitro genotoxic effects of the anticancer agent gemcitabine on the induction of chromosomal aberrations and sister-chromatid exchange in human lymphocytes.