VACCINES, cilt.11, sa.4, ss.1-11, 2023 (SCI-Expanded)
Abstract: Aim: We aimed to evaluate the awareness of pneumococcal vaccination (PCV13, PPSV23)
in general cardiology outpatient clinics and impact of physicians’ recommendations on vaccination
rates. Methods: This was a multicenter, observational, prospective cohort study. Patients over the
age of 18 from 40 hospitals in different regions of Turkey who applied to the cardiology outpatient
clinic between September 2022 and August 2021 participated. The vaccination rates were calculated within three months of follow-up from the admitting of the patient to cardiology clinics. Results: The
403 (18.2%) patients with previous pneumococcal vaccination were excluded from the study. The
mean age of study population (n = 1808) was 61.9 ± 12.1 years and 55.4% were male. The 58.7% had
coronary artery disease, hypertension (74.1%) was the most common risk factor, and 32.7% of the
patients had never been vaccinated although they had information about vaccination before. The main
differences between vaccinated and unvaccinated patients were related to education level and ejection
fraction. The physicians’ recommendations were positively correlated with vaccination intention
and behavior in our participants. Multivariate logistic regression analysis showed a significant
correlation between vaccination and female sex [OR = 1.55 (95% CI = 1.25–1.92), p < 0.001], higher
education level [OR = 1.49 (95% CI = 1.15–1.92), p = 0.002] patients’ knowledge [OR = 1.93 (95%
CI = 1.56–2.40), p < 0.001], and their physician’s recommendation [OR = 5.12 (95% CI = 1.92–13.68),
p = 0.001]. Conclusion: To increase adult immunization rates, especially among those with or at risk
of cardiovascular disease (CVD), it is essential to understand each of these factors. Even if during
COVID-19 pandemic, there is an increased awareness about vaccination, the vaccine acceptance level
is not enough, still. Further studies and interventions are needed to improve public vaccination rates.
Keywords: awareness of vaccination; pneumococcal vaccine; prevention of cardiovascular diseases