EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol.17, no.9, pp.1198-1204, 2013 (Peer-Reviewed Journal)
Article / Article
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
Science Citation Index Expanded, Scopus
Obstructive sleep apnea syndrome, Excessive day-time sleepiness, Epworth sleepiness scale, Hippocampus, MR volumetry, CENTRAL HYPOVENTILATION SYNDROME, BRAIN STRUCTURAL-CHANGES, HYPOPNEA SYNDROME, MAMMILLARY BODY, HYPOXIA, MORPHOLOGY, DISORDERS, SEVERITY, ACTIVATION, DEFICITS
BACKGROUND/AIM: The limbic system, specifically the hippocampus, plays a key role in controlling the sleep-wake cycle. Changes in these particular structures of the central nervous system have been suggested to be related to obstructive sleep apnea syndrome (OSAS). We hypothesized that reduced hippocampal volume is a risk factor for excessive daytime sleepiness (EDS) in OSAS.