Correlation between hippocampal volume and excessive daytime sleepiness in obstructive sleep apnea syndrome


Dusak A., Ursavas A., Hakyemez B., Gokalp G., Taskapilioglu O., Parlak M.

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol.17, no.9, pp.1198-1204, 2013 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 9
  • Publication Date: 2013
  • Journal Name: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.1198-1204
  • Keywords: Obstructive sleep apnea syndrome, Excessive day-time sleepiness, Epworth sleepiness scale, Hippocampus, MR volumetry, CENTRAL HYPOVENTILATION SYNDROME, BRAIN STRUCTURAL-CHANGES, HYPOPNEA SYNDROME, MAMMILLARY BODY, HYPOXIA, MORPHOLOGY, DISORDERS, SEVERITY, ACTIVATION, DEFICITS

Abstract

BACKGROUND/AIM: The limbic system, specifically the hippocampus, plays a key role in controlling the sleep-wake cycle. Changes in these particular structures of the central nervous system have been suggested to be related to obstructive sleep apnea syndrome (OSAS). We hypothesized that reduced hippocampal volume is a risk factor for excessive daytime sleepiness (EDS) in OSAS.