Correlation between hippocampal volume and excessive daytime sleepiness in obstructive sleep apnea syndrome

Dusak A., Ursavas A., Hakyemez B., Gokalp G., Taskapilioglu O., Parlak M.

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, cilt.17, sa.9, ss.1198-1204, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 9
  • Basım Tarihi: 2013
  • Dergi Adı: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1198-1204
  • Anahtar Kelimeler: Obstructive sleep apnea syndrome, Excessive day-time sleepiness, Epworth sleepiness scale, Hippocampus, MR volumetry, CENTRAL HYPOVENTILATION SYNDROME, BRAIN STRUCTURAL-CHANGES, HYPOPNEA SYNDROME, MAMMILLARY BODY, HYPOXIA, MORPHOLOGY, DISORDERS, SEVERITY, ACTIVATION, DEFICITS
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

BACKGROUND/AIM: The limbic system, specifically the hippocampus, plays a key role in controlling the sleep-wake cycle. Changes in these particular structures of the central nervous system have been suggested to be related to obstructive sleep apnea syndrome (OSAS). We hypothesized that reduced hippocampal volume is a risk factor for excessive daytime sleepiness (EDS) in OSAS.