Archives of Dermatological Research, cilt.318, sa.1, 2026 (SCI-Expanded, Scopus)
Acne excoriée (AE) is a psychodermatological condition involving compulsive manipulation of acne lesions, often accompanied by psychiatric comorbidities. This study examined emotional dysregulation, impulsivity, and psychopathological features in adolescents with AE compared with peers who had acne vulgaris (AV) without excoriation. In this cross-sectional study, 123 adolescents with AE and 89 age- and sex-matched AV controls were assessed using the Kiddie-Schedule for Affective Disorders and Schizophrenia (K-SADS-PL-DSM-5) and a standardized battery including the Difficulties in Emotion Regulation Scale (DERS), Barratt Impulsiveness Scale-Brief (BIS-Brief), Revised Child Anxiety and Depression Scale (RCADS; child and parent forms), Strengths and Difficulties Questionnaire (SDQ), Acne Quality of Life Scale (AQLS-11), and Clinical Global Impression (CGI). Acne severity was rated with the Global Acne Grading System (GAGS). Statistical analyses included independent t-tests with Benjamini–Hochberg FDR correction, effect sizes (Cohen’s d, 9% CI), and multivariable linear and logistic regression models. Adolescents with AE showed significantly greater emotion-regulation difficulties (DERS-Total: M = 76.5 ± 14.8 vs. 64.5 ± 8.6; d = 0.99, p < 0.001), higher psychopathology scores (RCADS-TAD, SDQ Total, CGI-S), and poorer acne-related quality of life (p < 0.001) than controls. Trait impulsivity measured by BIS-Brief did not differ significantly between groups (p = 0.27). In multivariable regression, AE status independently predicted higher DERS-Total scores after controlling for age, sex, acne severity (GAGS), depressive symptom severity (RCADS-MDD), and comorbid ADHD/MDD (β = − 0.50, p < 0.001). Logistic regression confirmed that DERS-Total and RCADS-Child scores significantly predicted AE status (AUC = 0.988, p < 0.001). Adolescents with AE experience marked emotional dysregulation and elevated psychiatric symptom burden, whereas global trait impulsivity is not elevated. Emotion-driven impulsivity under distress appears central to AE’s psychopathology. Routine psychiatric screening and emotion-regulation–focused interventions (e.g., HRT-skills, emotion-focused CBT, ACT) should be integrated into dermatologic care.