Head and neck squamous cell carcinoma of unknown primary: Neck dissection and radiotherapy or definitive radiotherapy


DEMİRÖZ ABAKAY C., Vainshtein J. M. , Koukourakis G. V. , Gutfeld O., Prince M. E. , Bradford C. R. , ...More

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, vol.36, no.11, pp.1589-1595, 2014 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 11
  • Publication Date: 2014
  • Doi Number: 10.1002/hed.23479
  • Journal Name: HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.1589-1595
  • Keywords: unknown primary, neck dissection, radiation therapy, human papillomavirus, LYMPH-NODE METASTASES, EPSTEIN-BARR-VIRUS, POLYMERASE-CHAIN-REACTION, LOCALLY ADVANCED HEAD, PRIMARY SITE, HUMAN-PAPILLOMAVIRUS, RADIATION-THERAPY, PRIMARY TUMOR, NASOPHARYNGEAL CARCINOMA, POSTOPERATIVE RADIATION

Abstract

BackgroundManagement of head and neck carcinoma from unknown primary (HNCUP) remains controversial, with neck dissection and radiotherapy (RT) or definitive RT both commonly used. The purpose of this study was to characterize HNCUP and retrospectively compare outcomes for patients treated with neck dissection+RT versus definitive RT.