Efficacy of Biphosphonates in Patients with Osteogenesis Imperfecta


EREN E. , Sincar S., Cakir E. D. P. , SAĞLAM H. , TARIM Ö. F.

GUNCEL PEDIATRI-JOURNAL OF CURRENT PEDIATRICS, vol.9, no.3, pp.122-126, 2011 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 9 Issue: 3
  • Publication Date: 2011
  • Title of Journal : GUNCEL PEDIATRI-JOURNAL OF CURRENT PEDIATRICS
  • Page Numbers: pp.122-126
  • Keywords: Osteogenesis imperfecta, fracture, biphosfonates, collagen

Abstract

Introduction: Osteogenesis imperfecta (OI) is a genetic disorder resulting in increased bone fragility due to defective collagen synthesis. Biphosfonates have been used in children with OI. Herein, we aimed to present clinical and laboratory features of the patients with OI and to evaluate response to biphosphonate therapy.