Capecitabine-induced cardiotoxicity mimicking myocardial infarction.

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Atıf İçin Kopyala

ŞENTÜRK T., Kanat O., Evrensel T., Aydinlar A.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, cilt.17, ss.277-80, 2009 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 17
• Basım Tarihi: 2009
• Doi Numarası: 10.1007/bf03086265
• Dergi Adı: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.277-80
• Anahtar Kelimeler: capecitabine, myocardial infarction, cardiotoxicity
• Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Capecitabine, a fluoropyrimidine derivative, is an orally administered drug that delivers 5-fluorouracil (5-FU) selectively to the tumour. The drug has demonstrated activity in metastatic colorectal cancer. We describe a male patient receiving capecitabine therapy with typical chest pain and electrocardiographic changes consistent with ST-segment elevation myocardial infarction. Capecitabine-induced cardiotoxicity may develop in patients who have had a previous episode of 5-FU-induced cardiotoxicity. Capecitabine-induced cardiotoxicity is a rare condition that may lead to diagnostic and therapeutic dilemmas. (Neth Heart J 2009;17:277-80.)