Serum monocyte chemoattractant protein-1 and monocyte adhesion molecules in type 1 diabetic patients with nephropathy

Kiyici, Sinem; Erturk, Erdinc; Budak, FERAH; Ersoy, Canan; Tuncel, Ercan; Duran, Cevdet; Oral, HALUK; Sigirci, Deniz; Imamoglu, Sazi

doi:10.1016/j.arcmed.2006.06.002

Serum monocyte chemoattractant protein-1 and monocyte adhesion molecules in type 1 diabetic patients with nephropathy

Atıf İçin Kopyala

Kiyici S., Erturk E., Budak F., Ersoy C., Tuncel E., Duran C., ...Daha Fazla

ARCHIVES OF MEDICAL RESEARCH, cilt.37, sa.8, ss.998-1003, 2006 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 37 Sayı: 8
Basım Tarihi: 2006
Doi Numarası: 10.1016/j.arcmed.2006.06.002
Dergi Adı: ARCHIVES OF MEDICAL RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.998-1003
Anahtar Kelimeler: diabetic nephropathy, MCP-1, adhesion molecules, ENDOTHELIAL DYSFUNCTION, EXPRESSION, RECRUITMENT, MACROPHAGES, ACTIVATION, CHEMOKINES, CYTOKINE, MELLITUS, MARKERS, LESIONS
Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Background. Monocyte chemoattractant protein (MCP)-1 is suggested to be implicated in the pathogenesis of diabetic nephropathy by activating and recruiting monocytes to the glomerulus via regulation of adhesion molecule expressions. The aim of this study was to test potential associations between serum concentrations of MCP-1, monocyte expression of Mac-1 and LFA-1 and nephropathy in type 1 diabetes mellitus.