Antibacterial activity of a phyto-complex of Rhus Coriaria on growth of early and late colonizer cariogenic bacteria

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Çelik Z. C., Elbek Çubukçu Ç., Tüzemen N. Ü., Özakın C.

International journal of traditional and complementary medicine research (Online), cilt.6, sa.2, ss.94-101, 2025 (TRDizin)

Özet

Abstract Objective: Rhus coriaria, commonly known as sumac, is a spice derived from the dried fruits of the Rhus genus. It supports oral health by potentially reducing bacterial growth and inflammation, making it a promising candidate for enhancing dental care products. The present study aimed to investigate the antimicrobial efficacy of a novel phytocomplex consisting a Rhus Coriaria extract, against early and late colonizers associated with cariogenic activity. Material-Method: Sonicated samples of experimental phyto-complex (G1-G5) contained aqueous extracts of Rhus coriaria at different concentrations of 0.0%; 6.25%; 12.5%; 18.75%; 25% and %5 propolis and adjunctive herbals. Antibacterial efficacy on Staphylococcus aureus, Escherichia coli, Streptococcus mitis, Streptococcus oralis, Streptococcus mutans and Scardovia wiggsiae was tested using the agar-well method. Results: All experimental groups containing Rhus coriaria extract (G2–G5) exhibited a concentration-dependent inhibition of growth for Staphylococcus aureus, Streptococcus mitis, Streptococcus oralis, Streptococcus mutans, and Scardovia wiggsiae, with the highest efficacy observed in G5 (25% extract). No inhibitory effects were observed against Escherichia coli across all formulations. Conclusion: A novel phyto-complex with the active ingredient Rhus Coriaria with antioxidant nature has demonstrated a concentration-dependent increasing inhibitory effect on Staphylococcus aureus and specific bacterial strains involved in the etiology of dental caries: Streptococcus mitis, Streptococcus oralis, Streptococcus mutans, and Scardovia wiggsiae. Keywords: Dental Caries, Rhus, Mouthwashes, Streptococcus Mutans, Scardovia Wiggsiae