Statin administration did not influence the progression of lung injury or associated organ failures in a cohort of patients with acute lung injury

Kor D. J., İŞÇİMEN R., YILMAZ M., Brown M. J., Brown D. R., Gajic O.

INTENSIVE CARE MEDICINE, cilt.35, sa.6, ss.1039-1046, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 6
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1007/s00134-009-1421-8
  • Dergi Adı: INTENSIVE CARE MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1039-1046
  • Anahtar Kelimeler: Acute lung injury, Acute respiratory distress syndrome, Multi-organ failure, HMG-CoA reductase inhibitors, Statins, COA REDUCTASE INHIBITOR, ISCHEMIA-REPERFUSION, HOSPITAL MORTALITY, VASCULAR-SURGERY, THERAPY, SEPSIS, PRAVASTATIN, SURVIVAL, MODEL
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Preclinical studies suggest that HMG-CoA reductase inhibitors (statins) may attenuate organ dysfunction. We evaluated whether statins are associated with attenuation of lung injury and prevention of associated organ failure in patients with ALI/ARDS.