Copy For Citation
Caner B., Kafa M. I., BEKAR A., Kurt M. A., Karli N., CANSEV M., ...More
NEUROLOGICAL RESEARCH, vol.34, no.3, pp.238-245, 2012 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
34
Issue:
3
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Publication Date:
2012
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Doi Number:
10.1179/1743132812y.0000000003
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Journal Name:
NEUROLOGICAL RESEARCH
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Page Numbers:
pp.238-245
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Keywords:
Citicoline, Choline, Cytidine, Sciatic nerve, Nerve regeneration, EXPERIMENTAL FOCAL ISCHEMIA, TRANSIENT CEREBRAL-ISCHEMIA, PHOSPHOLIPASE A(2), EMBOLIC STROKE, CITICOLINE, URIDINE, BRAIN, METABOLITES, PHOSPHOCHOLINE, STIMULATION
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Bursa Uludag University Affiliated:
Yes
Abstract
Objective: Topical cytidine-5'-diphosphocholine (CDP-choline) improves functional recovery and promotes nerve regeneration in sciatic nerve injury in rats. The aims of this study were to test whether systemic treatment with CDP-choline was effective in improving the recovery of injured sciatic nerve, and to determine whether the cytidine and/or choline moieties of CDP-choline contribute to its beneficial actions.