Effects of thiamine treatment on oxidative stress in experimental diabetes

Sarandol E., Tas S., Serdar Z., Dirican M.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.121, no.3, pp.235-241, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 121 Issue: 3
  • Publication Date: 2020
  • Doi Number: 10.4149/bll_2020_036
  • Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
  • Page Numbers: pp.235-241
  • Keywords: streptozotocin, diabetes mellitus, thiamine, oxidative stress, paraoxonase, HUMAN-SERUM PARAOXONASE, PHOSPHATE-ESTERS, VANADYL SULFATE, PLASMA, ARYLESTERASE, METABOLISM, COMPLICATIONS, DYSLIPIDEMIA, GLYCATION, TRANSPORT
  • Bursa Uludag University Affiliated: Yes

Abstract

AIM: Hyperglycemia, oxidative stress and hyperlipidemia are features of diabetes mellitus. Thiamine has beneficial effects on carbohydrate metabolism and it was proposed that this vitamin has antihyperlipidemic and antioxidant effects. Our aim was to investigate the effects of thiamine on oxidative stress and metabolic changes in streptozotocin (STZ) induced diabetic rats.