Effects of thiamine treatment on oxidative stress in experimental diabetes

Sarandol E., Tas S., Serdar Z., Dirican M.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.121, sa.3, ss.235-241, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 121 Sayı: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.4149/bll_2020_036
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.235-241
  • Anahtar Kelimeler: streptozotocin, diabetes mellitus, thiamine, oxidative stress, paraoxonase, HUMAN-SERUM PARAOXONASE, PHOSPHATE-ESTERS, VANADYL SULFATE, PLASMA, ARYLESTERASE, METABOLISM, COMPLICATIONS, DYSLIPIDEMIA, GLYCATION, TRANSPORT
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

AIM: Hyperglycemia, oxidative stress and hyperlipidemia are features of diabetes mellitus. Thiamine has beneficial effects on carbohydrate metabolism and it was proposed that this vitamin has antihyperlipidemic and antioxidant effects. Our aim was to investigate the effects of thiamine on oxidative stress and metabolic changes in streptozotocin (STZ) induced diabetic rats.