Protective Effects of Melatonin Therapy in Model for Neonatal Hyperoxic Lung Injury

Suleymanoglu, Selami; Cekmez, Ferhat; Cetinkaya, Merih; Tayman, Cuneyt; Canpolat, Fuat; Kafa, İLKER; Tanju, I.; Arziman, Ibrahim; Fidanci, M.; Tunc, Turan; Sarici, S.

Protective Effects of Melatonin Therapy in Model for Neonatal Hyperoxic Lung Injury

Suleymanoglu S., Cekmez F., Cetinkaya M., Tayman C., Canpolat F. E., Kafa İ. M., ...Daha Fazla

ALTERNATIVE THERAPIES IN HEALTH AND MEDICINE, cilt.20, sa.5, ss.24-29, 2014 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 20 Sayı: 5
Basım Tarihi: 2014
Dergi Adı: ALTERNATIVE THERAPIES IN HEALTH AND MEDICINE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.24-29
Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Context Bronchopulmonary dysplasia (BPD) is a common outcome of premature birth. Currently, no effective preventive therapy is available for BPD, but the major role of O-2 toxicity in the development of BPD has gained attention, particularly for developing new antioxidants for prevention. The major protective mechanism of melatonin (MT) includes free-radical scavenging activity and activation of the cyclooxygenase-prostoglandin enzyme system.