ALTERNATIVE THERAPIES IN HEALTH AND MEDICINE, cilt.20, sa.5, ss.24-29, 2014 (SCI-Expanded)
Context Bronchopulmonary dysplasia (BPD) is a common outcome of premature birth. Currently, no effective preventive therapy is available for BPD, but the major role of O-2 toxicity in the development of BPD has gained attention, particularly for developing new antioxidants for prevention. The major protective mechanism of melatonin (MT) includes free-radical scavenging activity and activation of the cyclooxygenase-prostoglandin enzyme system.