Protective Effects of Melatonin Therapy in Model for Neonatal Hyperoxic Lung Injury
ALTERNATIVE THERAPIES IN HEALTH AND MEDICINE, vol.20, no.5, pp.24-29, 2014 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 20 Issue: 5
- Publication Date: 2014
- Journal Name: ALTERNATIVE THERAPIES IN HEALTH AND MEDICINE
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.24-29
- Bursa Uludag University Affiliated: Yes
Abstract
Context Bronchopulmonary dysplasia (BPD) is a common outcome of premature birth. Currently, no effective preventive therapy is available for BPD, but the major role of O-2 toxicity in the development of BPD has gained attention, particularly for developing new antioxidants for prevention. The major protective mechanism of melatonin (MT) includes free-radical scavenging activity and activation of the cyclooxygenase-prostoglandin enzyme system.