The ATP Assay, but not the MTT assay, Detects Further Cytotoxicity of the Combination of Anthracycline-based Therapy with Histone Deacetylase Inhibitor (Valproic Acid) in Breast Cancer Cells

ARI, FERDA; Ikitimur, Elif; Ulukaya, Engin

The ATP Assay, but not the MTT assay, Detects Further Cytotoxicity of the Combination of Anthracycline-based Therapy with Histone Deacetylase Inhibitor (Valproic Acid) in Breast Cancer Cells

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ARI F., Ikitimur E. I., Ulukaya E.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.35, no.4, pp.293-299, 2010 (SCI-Expanded)

Publication Type: Article / Article
Volume: 35 Issue: 4
Publication Date: 2010
Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Page Numbers: pp.293-299
Bursa Uludag University Affiliated: Yes

Abstract

Purpose: It has been investigated that whether or not the combination of valproic acid (a histone deacetylase inhibitor) with anthracycline-based chemotherapy (FEC: 5-fluorouracil+epirubicine+ cyclophosphamide) would change the cytotoxic effects of FEC in breast cancer cells.