Effect of the P2Y(12) antagonist ticagrelor on neointimal hyperplasia in a rabbit carotid anastomosis model

Surer S., Toktas F., Ay D., Eris C., Yavuz S., Turk T., ...Daha Fazla

INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY, cilt.19, sa.2, ss.198-204, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1093/icvts/ivu087
  • Dergi Adı: INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.198-204
  • Anahtar Kelimeler: Intimal hyperplasia, Ticagrelor, Carotid artery, Rabbit model, INTIMAL HYPERPLASIA, CLOPIDOGREL, THROMBOSIS, INJURY
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

OBJECTIVES: In the present study, we aimed to deterimine the dose-related effects of ticagrelor, the first reversible inhibitor of the P2Y(12) receptor, found in smooth muscle cells as well as platelets, during neointimal hyperplasia in a rabbit carotid anastomosis model.