Intracerebroventricular injection of histamine induces the hypothalamic-pituitary-gonadal axis activation in male rats

Niaz N., Guvenc G., Altinbas B., Toker M. B. , Aydin B., Udum-Kucuksen D., ...More

BRAIN RESEARCH, vol.1699, pp.150-157, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 1699
  • Publication Date: 2018
  • Doi Number: 10.1016/j.brainres.2018.08.020
  • Title of Journal : BRAIN RESEARCH
  • Page Numbers: pp.150-157


Brain histamine holds a key position in the regulation of behavioral states, biological rhythms, body weight, energy metabolism, thermoregulation, fluid balance, stress and reproduction in female animals. However, it is not clear whether central histamine exerts any effect on hypothalamic-pituitary-testicular in male rats and if so, the involvement of type of central histamine receptors.