Expression of sex hormone-binding globulin, oxytocin receptor, caveolin-1 and p21 in leiomyoma
GYNECOLOGICAL ENDOCRINOLOGY, cilt.24, sa.2, ss.105-112, 2008 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 24 Sayı: 2
- Basım Tarihi: 2008
- Doi Numarası: 10.1080/09513590701690274
- Dergi Adı: GYNECOLOGICAL ENDOCRINOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.105-112
- Anahtar Kelimeler: co-localization, fibroma, oxytocin, oxytocin receptor, p21, sex hormone-binding globulin, MESSENGER-RIBONUCLEIC-ACID, UTERINE LEIOMYOMAS, CANCER-CELLS, PROLIFERATION, PATHOGENESIS, ENDOMETRIUM, MYOMETRIUM, PROTEIN, GROWTH, LOCALIZATION
- Bursa Uludağ Üniversitesi Adresli: Evet
Özet
Background. Interaction of sex hormone-binding globulin (SHBG) and oxytocin (OT) is among the factors that control smooth muscle proliferation and tumor growth through the oxytocin receptor (OTR). Also, a close functional interaction of OTR and caveolin-1 has been shown to modulate cell growth and proliferation.