Akademik Veri Yönetim Sistemi
KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, cilt.18, 2008 (SCI-Expanded)
The recent advances of molecular genetics in basic science, the number of genetic studies in the psychiatric field has been increasing in the last years. Clinical genetic studies revealed that not only schizophrenia and mood disorders but also some of the neurotic disorders such as anxiety disorders have a genetic component. Genetic knowledge obtained by genetic research must be applicable in clinical practice. Molecular genetic positional and candidate gene approaches are being used for the genetic dissection of schizophrenia and bipolar disorder. This will have a major impact on our understanding of disease pathophysiology and will provide important opportunities to investigate the interaction between genetic and environmental factors involved in pathogenesis. The genetic mutations and chromosomal regions related to schizophrenia and bipolar disorder have been evaluated in this review.