BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, cilt.19, sa.12, ss.3259-3263, 2009 (SCI-Expanded)
Novel Tetrac analogs were synthesized and then tested. Anti-angiogenesis efficacy was carried out using the Chick Chorioallantoic Membrane (CAM) model and the mouse matrigel model for angiogenesis. Pharmacological activities showed Tetrac can accommodate numerous modifications and maintain anti-angiogenesis activity. (C) 2009 Published by Elsevier Ltd.