In order to evaluate the value of Tc-99m (V) DMSA in the diagnostic evaluation of various malignancies, 15 patients were undergone scintigraphy with Tc-99m (V) DMSA. The patients were all male and the mean age was 59.3+/-7.4. 12 of the cases were primary and metastatic lung cancers, 2 were renal cell carcinomas and 1 of them was gastric cancer. Total body imaging was done in all the. patients after 2 hours of radionuclide administration and SPECT was performed in patients with lung lesions. The patients were also evaluated with bone scintigraphy, ultrasonography and computed tomography of the involved organ and the results were compared.