EXPERIMENTAL NEUROLOGY, vol.317, pp.1-9, 2019 (SCI-Expanded)
Article / Article
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Mitoquinone, NF-E2-related factor 2, Prohibitin 2, Optic atrophy 1, Blood-brain barrier disruption, Subarachnoid hemorrhage, POSSIBLE INVOLVEMENT, INJURY, PROHIBITINS, INHIBITION, APOPTOSIS, NUCLEAR, DISEASE, EDEMA
Bursa Uludag University Affiliated:
Background and purpose: Mitochondrial dysfunction is involved in the mechanism of early brain injury (EBI) following subarachnoid hemorrhage (SAH). Blood-brain barrier disruption is a devastating outcome in the early stage of SAH. In this study, we aimed to investigate the role of a mitochondria-related drug Mitoquinone (MitoQ) in blood-brain barrier disruption after SAH in rats.