Tetraiodothyroacetic Acid (Tetrac) and Nanoparticulate Tetrac Arrest Growth of Medullary Carcinoma of the Thyroid

Yalcin, M.; Dyskin, E.; Lansing, L.; Bharali, D.; Mousa, S.; Bridoux, A.; Hercbergs, A.; Lin, H.; Davis, F.; Glinsky, G.; Glinskii, A.; Ma, J.; Davis, P.; Mousa, S.

doi:10.1210/jc.2009-1926

Tetraiodothyroacetic Acid (Tetrac) and Nanoparticulate Tetrac Arrest Growth of Medullary Carcinoma of the Thyroid

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Yalcin M., Dyskin E., Lansing L., Bharali D. J., Mousa S. S., Bridoux A., ...More

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, vol.95, no.4, pp.1972-1980, 2010 (SCI-Expanded)

Publication Type: Article / Article
Volume: 95 Issue: 4
Publication Date: 2010
Doi Number: 10.1210/jc.2009-1926
Journal Name: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1972-1980
Bursa Uludag University Affiliated: No

Abstract

Context: Tetraiodothyroacetic acid (tetrac) blocks angiogenic and tumor cell proliferation actions of thyroid hormone initiated at the cell surface hormone receptor on integrin alpha v beta 3. Tetrac also inhibits angiogenesis initiated by vascular endothelial growth factor and basic fibroblast growth factor.