Tetraiodothyroacetic Acid (Tetrac) and Nanoparticulate Tetrac Arrest Growth of Medullary Carcinoma of the Thyroid


Yalcin M., Dyskin E., Lansing L., Bharali D. J. , Mousa S. S. , Bridoux A., ...More

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, vol.95, no.4, pp.1972-1980, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 95 Issue: 4
  • Publication Date: 2010
  • Doi Number: 10.1210/jc.2009-1926
  • Title of Journal : JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
  • Page Numbers: pp.1972-1980

Abstract

Context: Tetraiodothyroacetic acid (tetrac) blocks angiogenic and tumor cell proliferation actions of thyroid hormone initiated at the cell surface hormone receptor on integrin alpha v beta 3. Tetrac also inhibits angiogenesis initiated by vascular endothelial growth factor and basic fibroblast growth factor.