Tetraiodothyroacetic Acid (Tetrac) and Nanoparticulate Tetrac Arrest Growth of Medullary Carcinoma of the Thyroid


Yalcin M., Dyskin E., Lansing L., Bharali D. J., Mousa S. S., Bridoux A., ...More

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, vol.95, no.4, pp.1972-1980, 2010 (SCI-Expanded) identifier identifier identifier

Abstract

Context: Tetraiodothyroacetic acid (tetrac) blocks angiogenic and tumor cell proliferation actions of thyroid hormone initiated at the cell surface hormone receptor on integrin alpha v beta 3. Tetrac also inhibits angiogenesis initiated by vascular endothelial growth factor and basic fibroblast growth factor.