Effects of Calcineurin Inhibitors on Paraoxonase and Arylesterase Activity After a Kidney Transplant


Kahvecioglu S., ERSOY A. , GÜLLÜLÜ M. , Dirican M.

EXPERIMENTAL AND CLINICAL TRANSPLANTATION, vol.12, no.4, pp.334-342, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 4
  • Publication Date: 2014
  • Doi Number: 10.6002/ect.2013.0110
  • Title of Journal : EXPERIMENTAL AND CLINICAL TRANSPLANTATION
  • Page Numbers: pp.334-342
  • Keywords: Cardiovascular, Cyclosporine, Oxidative stress, Tacrolimus, LOW-DENSITY-LIPOPROTEIN, OXIDATIVE STRESS, RENAL-TRANSPLANTATION, IMMUNOSUPPRESSIVE THERAPY, ENDOTHELIAL FUNCTION, CYCLOSPORINE-A, GLIAL-CELLS, RECIPIENTS, TACROLIMUS, PLASMA

Abstract

Objectives: Cardiovascular disease is a common cause of morbidity and mortality in patients with chronic kidney failure, before and after a kidney transplant. Oxidation of lipoproteins that contain apolipoprotein B may contribute to the initiation of atherosclerosis. Paraoxonase may prevent cardiovascular disease. We compared the effects of different calcineurin inhibitors on risk factors for cardiovascular disease in kidney transplant recipients.