Evaluation of intra-articular collagenase, TIMP-1, and TNF-alpha levels before and after anterior cruciate ligament reconstruction

AKESEN B., Demirag B., BUDAK F.

ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA, vol.43, no.3, pp.214-218, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 3
  • Publication Date: 2009
  • Doi Number: 10.3944/aott.2009.214
  • Journal Name: ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.214-218
  • Keywords: Anterior cruciate ligament/injuries, matrix metalloproteinases, knee joint, synovial fluid, tissue inhibitor of metalloproteinases, tumor necrosis factor-alpha, SYNOVIAL-FLUID CYTOKINE, MATRIX METALLOPROTEINASES, TISSUE INHIBITORS, OSTEOARTHRITIS, TENDON, KNEE, INJURY, TUNNEL, JOINT, DOGS
  • Bursa Uludag University Affiliated: Yes

Abstract

Objectives: We investigated intra-articular levels of collagenase, which presumably promotes bone-tendon healing, and collagenase mediators involved in its production (tumor necrosis factor-alpha, TNF-alpha) and inhibition (TIMP-1 enzyme) in patients following anterior cruciate ligament (ACL) reconstruction.