Evaluation of serum iron and iron binding capacity in cows with paratuberculosis

Senturk S., Metcitoglu Z., Ulgen M., Borum E., Temizel E., KASAP S.

TIERAERZTLICHE PRAXIS AUSGABE GROSSTIERE NUTZTIERE, cilt.37, sa.6, ss.375-378, 2009 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 6
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1055/s-0038-1623829
  • Dergi Adı: TIERAERZTLICHE PRAXIS AUSGABE GROSSTIERE NUTZTIERE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.375-378
  • Anahtar Kelimeler: Cattle, paratuberculosis, haematocrit, haemoglobin, erythrocyte count, iron, iron binding capacity, MYCOBACTERIUM-PARATUBERCULOSIS, MACROPHAGES, ACQUISITION, AVIUM, PARTICIPATION, TUBERCULOSIS, METABOLISM, MECHANISM, GROWTH, INVIVO
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Objective: The purpose of the study was to evaluate the results of routine haematological, serum iron and iron binding capacity analyses in cattle with Mycobacterium avium subsp. paratuberculosis (MAP) infection. Material and methods: Thirty-eight cows were included in the study. An ELISA for MAP, intradermal Johnin test and microscopic examination of the animals faecal smears for acid fast organisms were performed. According to the results 19 cows (4-8 years old) were found positive and 19 cows (4-7 years old) from the same herd were negative and served as control group. In all cows routine haematological values as well as serum iron level and iron binding capacity were evaluated. Results: When compared with control animals, routine haematological values including haematocrit, haemoglobin and erythrocyte counts were significantly (p < 0.05) lower in positive cows. Also serum iron level (p < 0,01) and iron binding capacity (p < 0.01) were significantly lower in positive cows than in the control group. Conclusion: As a result, these parameters can be important for the mechanism of the pathogenesis of paratuberculosis.