Comparison of Asymmetric Dimethyl Arginine and Oxidative Stress Parameters in Obese Dogs and Dogs with Clinically Normal Body Condition Based on Routine Hemogram and Serum Biochemicals

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Cihan H., Tunca M.

INDIAN JOURNAL OF ANIMAL RESEARCH, no.8, pp.1-6, 2023 (SCI-Expanded)

  • Publication Type: Article / Article
  • Publication Date: 2023
  • Journal Name: INDIAN JOURNAL OF ANIMAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database
  • Page Numbers: pp.1-6
  • Bursa Uludag University Affiliated: Yes

Abstract

Background: Obesity, which has recently created many problems in humans and animals, is stated as being above 15-20% of normal body weight. This condition is commonly classified using body condition scoring in dogs. This study compared oxidative stress (malondialdehyde, catalase, superoxide dismutase), asymmetric dimethylarginine (ADMA), routine hemograms and biochemicals in obese dogs and dogs with normal body conditions. 

Methods: Blood samples were taken from 20 normal body condition and 20 obese dogs. ADMA, oxidative stress and routine hematologic and biochemical parameters were evaluated. 

Result: Platelet count (p = 0.009), blood urea nitrogen (p <0.001), cholesterol (p = 0.006), ADMA (p <0.05) and malondialdehyde (p<0.001) were statistically high, while superoxide dismutase and catalase (p <0.001 and p <0.001, respectively) were statistically low in the obese group than the normal body condition group. As a result, we think the interpretation of the indicated biomarkers may help evaluate obesity and related pathologies in dogs, monitor treatment, or help prevent potential problems associated with obesity.