PARKINSON'S DISEASE: IS IT ACTUALLY AN INFLAMMATORY DISORDER?

Buyukkoyuncu Pekel N., Yildiz D., SIĞIRLI D., Yabaci A., Seferoglu M., Gunes A.

TURKISH JOURNAL OF GERIATRICS-TURK GERIATRI DERGISI, vol.21, no.4, pp.483-489, 2018 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 4
  • Publication Date: 2018
  • Doi Number: 10.31086/tjgeri.2018.52
  • Journal Name: TURKISH JOURNAL OF GERIATRICS-TURK GERIATRI DERGISI
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.483-489
  • Keywords: Parkinson disease, Inflammation, Echocardiography, EPICARDIAL ADIPOSE-TISSUE, C-REACTIVE PROTEIN, FAT THICKNESS, RATIO, NEUTROPHIL/LYMPHOCYTE, NEUTROPHIL
  • Bursa Uludag University Affiliated: Yes

Abstract

Introduction: Parkinson's disease is the second leading neurodegenerative disease worldwide; however, its pathogenesis remains unclear. Recently, the neuroinflammation theory, one of the theories explaining the pathogenesis of Parkinson's disease, has become prominent. We investigated the relationship between Parkinson's disease and inflammatory markers including epicardial adipose tissue thickness, neutrophil-lymphocyte ratio, and thrombocyte-lymphocyte ratio.