PARKINSON'S DISEASE: IS IT ACTUALLY AN INFLAMMATORY DISORDER?

Buyukkoyuncu Pekel N., Yildiz D., SIĞIRLI D., Yabaci A., Seferoglu M., Gunes A.

TURKISH JOURNAL OF GERIATRICS-TURK GERIATRI DERGISI, cilt.21, sa.4, ss.483-489, 2018 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 4
  • Basım Tarihi: 2018
  • Doi Numarası: 10.31086/tjgeri.2018.52
  • Dergi Adı: TURKISH JOURNAL OF GERIATRICS-TURK GERIATRI DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.483-489
  • Anahtar Kelimeler: Parkinson disease, Inflammation, Echocardiography, EPICARDIAL ADIPOSE-TISSUE, C-REACTIVE PROTEIN, FAT THICKNESS, RATIO, NEUTROPHIL/LYMPHOCYTE, NEUTROPHIL
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Introduction: Parkinson's disease is the second leading neurodegenerative disease worldwide; however, its pathogenesis remains unclear. Recently, the neuroinflammation theory, one of the theories explaining the pathogenesis of Parkinson's disease, has become prominent. We investigated the relationship between Parkinson's disease and inflammatory markers including epicardial adipose tissue thickness, neutrophil-lymphocyte ratio, and thrombocyte-lymphocyte ratio.