Neoadjuvant chemotherapy-induced changes in immunohistochemical expression of estrogen receptor, progesterone receptor, HER2, and Ki-67 in patients with breast cancer

Avci N., DELİGÖNÜL A., TOLUNAY Ş., ÇUBUKÇU E., Olmez O. F., Ulas A., ...Daha Fazla

JOURNAL OF BUON, cilt.20, sa.1, ss.45-49, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 1
  • Basım Tarihi: 2015
  • Dergi Adı: JOURNAL OF BUON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.45-49
  • Anahtar Kelimeler: breast cancer, estrogen/progesterone receptor, HER2, immunohistochemistry, Ki-67, neoadjuvant chemotherapy, KI67
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Purpose: The impact of neoadjuvant chemotherapy (NACT) on immunohistochemical markers in breast cancer specimens remains controversial. We designed the current study to investigate the potential changes in estrogen receptor (ER), progesterone receptor (PR), HER2, and Ki-67 expression before and after NACT in a cohort of Turkish patients with breast cancer.