SENSORS, cilt.25, sa.11, 2025 (SCI-Expanded)
This review explores the application of nanomaterial-based sensing systems for precisely detecting neuropharmaceutical compounds and neurotransmitters, delving into the connections between nanotechnology and neuropharmacology. Nanotechnology appears as a promising solution for many significant challenges posed by the complexities of the brain's biochemical nature. Using nanoscale materials, scientists have created novel sensors with high selectivity, sensitivity, and adaptability. Developing neuropharmaceutical compounds and monitoring their side effects on our neurological system raised the need for these nanomaterial-based sensors. In this review, we demonstrate the effectiveness of these technologies in real-time neuroactive compound detection and monitoring by illuminating the underlying principles through an examination of significant studies and recent developments. This review also highlights collaborative efforts at the intersection of nanotechnology and neuropharmacology and their direct and indirect effects on the understanding and controlling several neurological disorders. This review covers both sensors under research and those already applied in vivo or clinical monitoring of drug side effects.