DETERMINATION OF ANTI-UREASE ACTIVITY OF PROPOLIS FROM MARMARA REGION OF TURKEY Türkiye'nin Marmara Bölgesinden Elde Edilen Bazi Propolislerin Anti-üreaz Aktivitesinin Belirlenmesi


Creative Commons License

Can Z., KARA Y., KOLAYLI S., ÇAKMAK İ.

Uludag Aricilik Dergisi, vol.22, no.1, pp.25-30, 2022 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.31467/uluaricilik.1068885
  • Journal Name: Uludag Aricilik Dergisi
  • Journal Indexes: Scopus, Academic Search Premier
  • Page Numbers: pp.25-30
  • Keywords: Enyzme inhibition, Propolis, Urease
  • Bursa Uludag University Affiliated: Yes

Abstract

© 2022 Uludag Aricilik Dergisi. All rights reserved.Propolis is a natural product collected by honeybees from plants especially flowers and buds by mixing with wax and resin and used for many purposes in hive. It is known that propolis has been used in the treatment of various diseases in traditional medicine for many years and has biological activities such as antioxidant, antimicrobial, antiulcer, antitumor, anti-inflammatory. There is increasing interest in alternative approaches to inhibit Helicobacter pylori (H. pylori) and thereby treat many gastric diseases. This study investigated various properties of raw propolis samples from the Marmara region of Turkey. Anti-urease activity was investigated in propolis samples. The anti-urease activity of IC50 values ranged from 1.110 to 5.870 mg/mL. As a result, it can be said that propolis extract is a good inhibitor that can be used in the treatment of H. pylori to improve human health.