Current Approaches for Marginal Donor Usage in Kidney Transplantation

Ayar Y., ERSOY A.

TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL, cilt.25, ss.41-52, 2016 (ESCI) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 25
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5262/tndt.2016.06
  • Dergi Adı: TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.41-52
  • Anahtar Kelimeler: Kidney transplantation, Graft survival, Marginal donor, Organ shortage, EXPANDED CRITERIA DONORS, INTERMEDIATE-TERM OUTCOMES, COLD-STORAGE, RENAL-TRANSPLANTATION, CIRCULATORY-DEATH, SCORING SYSTEM, RISK INDEX, MACHINE PERFUSION, SURVIVAL BENEFIT, DECEASED DONORS
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Organ shortage is a significant problem for patients with end-stage renal disease seeking kidney transplantation despite efforts for increasing living kidney donation and strategies such as paired exchange. The donor pool can be expanded using more extended criteria donor (ECD) kidneys. Although graft survival in ECD transplants is shorter, these kidneys still provide a survival advantage over maintenance dialysis. The use of ECD kidneys is necessary to maintain current rates of transplantation. In United States, the Kidney Transplantation Committee is presented the United National Organ Sharing Board of Directors a document which calls for the allocation process to start by grading the kidney via a kidney donor profile index. Recently, major scientific societies related to renal transplantation in Spain have developed a consensus for the acceptance criteria of ECD kidneys and for the common actions to standardize access to transplantation with these donors nationwide. Herein, we aim to review the current strategies associated with marginal donor usage.