Aqueous humor adrenomedullin levels differ in patients with different types of glaucoma

EVEREKLİOĞLU C., Doganay S., Er H., Yurekli M.

JAPANESE JOURNAL OF OPHTHALMOLOGY, cilt.46, sa.2, ss.203-208, 2002 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 2
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1016/s0021-5155(01)00501-9
  • Dergi Adı: JAPANESE JOURNAL OF OPHTHALMOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.203-208
  • Bursa Uludağ Üniversitesi Adresli: Hayır

Özet

Purpose: Adrenomedullin is a multifunctional 52 amino acid large peptide. Recent studies have reported that it is expressed in the iris-ciliary body in the eye and that it decreases intraocular pressure (IOP) by increasing outflow facility via specific adrenomedullin receptors, suggesting a role for this peptide in controlling IOP. In the present study, we aimed to explore clinically the possible involvement of adrenomedullin in the pathophysiology of glaucoma.