Aqueous humor adrenomedullin levels differ in patients with different types of glaucoma
JAPANESE JOURNAL OF OPHTHALMOLOGY, vol.46, no.2, pp.203-208, 2002 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 46 Issue: 2
- Publication Date: 2002
- Doi Number: 10.1016/s0021-5155(01)00501-9
- Journal Name: JAPANESE JOURNAL OF OPHTHALMOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.203-208
- Bursa Uludag University Affiliated: No
Abstract
Purpose: Adrenomedullin is a multifunctional 52 amino acid large peptide. Recent studies have reported that it is expressed in the iris-ciliary body in the eye and that it decreases intraocular pressure (IOP) by increasing outflow facility via specific adrenomedullin receptors, suggesting a role for this peptide in controlling IOP. In the present study, we aimed to explore clinically the possible involvement of adrenomedullin in the pathophysiology of glaucoma.