Aqueous humor adrenomedullin levels differ in patients with different types of glaucoma

EVEREKLİOĞLU C., Doganay S., Er H., Yurekli M.

JAPANESE JOURNAL OF OPHTHALMOLOGY, vol.46, no.2, pp.203-208, 2002 (SCI-Expanded) identifier identifier identifier


Purpose: Adrenomedullin is a multifunctional 52 amino acid large peptide. Recent studies have reported that it is expressed in the iris-ciliary body in the eye and that it decreases intraocular pressure (IOP) by increasing outflow facility via specific adrenomedullin receptors, suggesting a role for this peptide in controlling IOP. In the present study, we aimed to explore clinically the possible involvement of adrenomedullin in the pathophysiology of glaucoma.