Aqueous humor adrenomedullin levels differ in patients with different types of glaucoma

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EVEREKLİOĞLU C., Doganay S., Er H., Yurekli M.

JAPANESE JOURNAL OF OPHTHALMOLOGY, vol.46, no.2, pp.203-208, 2002 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 46 Issue: 2
• Publication Date: 2002
• Doi Number: 10.1016/s0021-5155(01)00501-9
• Journal Name: JAPANESE JOURNAL OF OPHTHALMOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.203-208
• Bursa Uludag University Affiliated: No

Abstract

Purpose: Adrenomedullin is a multifunctional 52 amino acid large peptide. Recent studies have reported that it is expressed in the iris-ciliary body in the eye and that it decreases intraocular pressure (IOP) by increasing outflow facility via specific adrenomedullin receptors, suggesting a role for this peptide in controlling IOP. In the present study, we aimed to explore clinically the possible involvement of adrenomedullin in the pathophysiology of glaucoma.