Detection of CYP1A1 and GSTP1 gene polymorphisms in bladder cancer patients in a Turkish population using a polymerase chain reaction-restriction fragment length polymorphism method


Altunkol A., Savas M., DİLMEÇ F., Utangac M. M. , Abat D., Gumus K., ...More

TURKISH JOURNAL OF UROLOGY, vol.44, no.2, pp.125-131, 2018 (Journal Indexed in ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 2
  • Publication Date: 2018
  • Doi Number: 10.5152/tud.2018.23571
  • Title of Journal : TURKISH JOURNAL OF UROLOGY
  • Page Numbers: pp.125-131

Abstract

Objective: Understanding genetic polymorphisms might facilitate the analysis of differences between individuals in their susceptibility to developing cancers as a result of environmental carcinogens. Skin, lung, colon and bladder cancers emerge from biological defects in GSTM1, GSTT1 and GSTP1 gene expressions. In this study, we aimed to investigate whether there was an association between CYP1A1 and GSTP1 gene polymorphisms and bladder cancer in a Turkish population.