Effects of Different Onset Times of Early Caffeine Treatment on Mesenteric Tissue Oxygenation and Necrotizing Enterocolitis: A Prospective, Randomized Study

ÖZKAN H., Cetinkaya M., Cakir S. Ç., Saglam O., KÖKSAL F. N.

AMERICAN JOURNAL OF PERINATOLOGY, cilt.40, sa.1, ss.28-34, 2023 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 1
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1055/s-0041-1727157
  • Dergi Adı: AMERICAN JOURNAL OF PERINATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.28-34
  • Anahtar Kelimeler: caffeine, mesenteric tissue oxygen saturation, necrotizing enterocolitis, newborn
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Objective Caffeine treatment is routinely used in premature infants to prevent development of apnea and bronchopulmonary dysplasia. Although a limited number of studies have reported that early caffeine treatment may cause development of necrotizing enterocolitis (NEC) by reducing mesenteric blood flow, this issue is still under discussion. The aim of this study is to investigate the possible effect of different onset times of early caffeine treatment on mesenteric tissue oxygen saturation and NEC development in premature infants.