Association Between Level of Hepatitis D Virus RNA at Week 24 of Pegylated Interferon Therapy and Outcome

KESKİN O., Wedemeyer H., Tuzun A., Zachou K., Deda X., Dalekos G. N., ...More

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, vol.13, no.13, pp.2342-2351, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 13
  • Publication Date: 2015
  • Doi Number: 10.1016/j.cgh.2015.05.029
  • Journal Name: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2342-2351
  • Keywords: Chronic Delta Hepatitis, Pegylated Interferon Treatment, Treatment Outcome Prediction, On-Treatment HDV RNA, CHRONIC DELTA-HEPATITIS, PEGINTERFERON ALPHA-2A, KINETICS, INTERLEUKIN-28B, POLYMORPHISMS, RIBAVIRIN, EFFICACY, HBSAG, DRUG
  • Bursa Uludag University Affiliated: Yes

Abstract

BACKGROUND & AIMS: Interferon is the only effective treatment for chronic hepatitis D virus (HDV) infection. No rules have been set for stopping treatment based on viral kinetics. We analyzed data from an international study of hepatitis D treatment to identify factors associated with outcomes of pegylated interferon treatment, with and without adefovir.