Association Between Level of Hepatitis D Virus RNA at Week 24 of Pegylated Interferon Therapy and Outcome

KESKİN O., Wedemeyer H., Tuzun A., Zachou K., Deda X., Dalekos G. N., ...Daha Fazla

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, cilt.13, sa.13, ss.2342-2351, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13 Sayı: 13
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.cgh.2015.05.029
  • Dergi Adı: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2342-2351
  • Anahtar Kelimeler: Chronic Delta Hepatitis, Pegylated Interferon Treatment, Treatment Outcome Prediction, On-Treatment HDV RNA, CHRONIC DELTA-HEPATITIS, PEGINTERFERON ALPHA-2A, KINETICS, INTERLEUKIN-28B, POLYMORPHISMS, RIBAVIRIN, EFFICACY, HBSAG, DRUG
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

BACKGROUND & AIMS: Interferon is the only effective treatment for chronic hepatitis D virus (HDV) infection. No rules have been set for stopping treatment based on viral kinetics. We analyzed data from an international study of hepatitis D treatment to identify factors associated with outcomes of pegylated interferon treatment, with and without adefovir.