Copy For Citation
Koza G., Ozcan S., Şahin E., Balci M.
TETRAHEDRON, vol.65, pp.5973-5976, 2009 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
65
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Publication Date:
2009
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Doi Number:
10.1016/j.tet.2009.05.090
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Journal Name:
TETRAHEDRON
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Page Numbers:
pp.5973-5976
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Keywords:
Pyrimidinone, Furopyrimidinone, Acyl azide, Acyl hydrazide, Curtius rearrangement, CALCIUM-CHANNEL BLOCKERS, ACID-ESTERS, DIHYDROPYRIMIDINE, CHEMISTRY, REVISION
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Bursa Uludag University Affiliated:
No
Abstract
We hereby report the first preparation of the 3,4-dihydrofuro[3,2-d]pyrimidin-2(1H)-one skeleton formed by two controlled Curtius rearrangements of the corresponding acyl azides, prepared from 2-(2-methoxy-2-oxoethyl)furan-3-carboxylate via the hydrazide. Rearrangement of the acyl azides followed by trapping by nucleophiles and intramolecular trapping provided the target compounds. (C) 2009 Elsevier Ltd. All rights reserved.