Olive leaf extract containing oleuropein modulates the cytotoxic effect of epirubicin on breast cancer cells depending on the cell line

Korkmaz S., SARIMAHMUT M., Ozel M. Z., Ulukaya E.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.41, sa.6, ss.385-392, 2016 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 41 Sayı: 6
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1515/tjb-2016-0117
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.385-392
  • Anahtar Kelimeler: Olive leaf extract, Breast cancer cell lines, Apoptosis, Cytotoxicity, Epirubicin, MEDITERRANEAN DIET, BITTER PRINCIPLE, IN-VITRO, APOPTOSIS, PHYTOCHEMICALS, COMBINATION, INHIBITION, ACTIVATION, RESISTANCE, RISK
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Objective: Epidemiologic studies showed that nutrition plays a role in incidence of cancer. However, little is known if nutrition also modulates the effect of chemotherapeutics. For this purpose, the present study investigates the cytotoxic effect of olive leaf extract and its combination with epirubicin.