Selective serotonin reuptake inhibitors and manic switch: A pharmacovigilance and pharmacodynamical study.

Çiray R. O., Halaç E., Turan S., Tunçtürk M., Özbek M., Ermiş Ç.

Asian journal of psychiatry, cilt.66, ss.102891, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 66
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.ajp.2021.102891
  • Dergi Adı: Asian journal of psychiatry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Psycinfo
  • Sayfa Sayıları: ss.102891
  • Anahtar Kelimeler: Bipolar disorder, Manic switch, Pharmacodynamical study, Elevated mood, antidepressants, ANTIDEPRESSANT TREATMENT, BIPOLAR DISORDER, MAJOR DEPRESSION, SCOPOLAMINE, MOOD, CHILDREN, EFFICACY, SLEEP
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Background: There is still no approved mechanism of manic switch in bipolar disorder, yet many selective serotonin reuptake inhibitors were accused for this important adverse event. Therefore, we aimed to investigate to estimate SSRI' s risk for reporting mania and elevated mood using FEARS database and investigate receptor mechanisms involved.