Impact of Storage Period on CD4(+)/CD8(+) T Lymphocyte Ratio in Erythrocyte Suspensions


Bal S. H. , Kumas L. T. , HEPER Y. , BUDAK F. , Goral G., Can F. E. , ...More

TURKISH JOURNAL OF IMMUNOLOGY, vol.8, no.2, pp.44-49, 2020 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 2
  • Publication Date: 2020
  • Doi Number: 10.25002/tji.2020.1242
  • Title of Journal : TURKISH JOURNAL OF IMMUNOLOGY
  • Page Numbers: pp.44-49

Abstract

Introduction: Some immunologic changes in the recipient derived by allogeneic blood transfusion (ABT) are called Transfusion Related Immune Modulation (TRIM). Despite the exact mechanisms of these changes are not known, it is thought that ABT causes a decrease of CD4/CD8 ratio in the recipient. This study aimed to determine the CD4/CD8 ratio in stored erythrocyte suspensions (ES) and to obtain new information about TRIM mechanisms.