Impact of Storage Period on CD4(+)/CD8(+) T Lymphocyte Ratio in Erythrocyte Suspensions

Bal S. H., Kumas L. T., HEPER Y., BUDAK F., Goral G., Can F. E., ...Daha Fazla

TURKISH JOURNAL OF IMMUNOLOGY, cilt.8, sa.2, ss.44-49, 2020 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.25002/tji.2020.1242
  • Dergi Adı: TURKISH JOURNAL OF IMMUNOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.44-49
  • Anahtar Kelimeler: CD4-CD8 ratio, erythrocyte suspension, erythrocyte transfusion, immunomodulation, transfusion, RED-CELL STORAGE, BLOOD-TRANSFUSION, STORED-BLOOD, TRANSPLANTATION, INCREASES, INFECTION
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Introduction: Some immunologic changes in the recipient derived by allogeneic blood transfusion (ABT) are called Transfusion Related Immune Modulation (TRIM). Despite the exact mechanisms of these changes are not known, it is thought that ABT causes a decrease of CD4/CD8 ratio in the recipient. This study aimed to determine the CD4/CD8 ratio in stored erythrocyte suspensions (ES) and to obtain new information about TRIM mechanisms.