Serum leptin and ghrelin levels in response to methylprednisolone injection in healthy dogs.

Yilmaz Z., Ilcol Y. O., Golcu E.

Research in veterinary science, cilt.82, sa.2, ss.187-94, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 82 Sayı: 2
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.rvsc.2006.07.005
  • Dergi Adı: Research in veterinary science
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.187-94
  • Anahtar Kelimeler: leptin, ghrelin, glucocorticoid, methylprednisolone, dog, TERM SECRETORY REGULATION, GROWTH-HORMONE, PLASMA LEPTIN, ACTIVE FORM, OBESE GENE, CORTISOL, INSULIN, GLUCOCORTICOIDS, DEXAMETHASONE, ADIPOSITY
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

The aim of this study was to investigate the effects of methylprednisolone treatment on serum leptin and ghrelin levels in healthy dogs (n = 40). After 14 h of fasting, the dogs were injected intramuscularly with saline (control group) or methylprednisolone (1, 5 or 10 mg/ kg). Blood samples were collected prior to (baseline) and 2, 3, 4, 8, 12 and 24 h subsequent to the treatments. Serum leptin and ghrelin were measured by radioimmunoassay.