Serum Iron Status and Its Relation with Haematological Indexes Before and After Parturition in Sheep


CİHAN H. , TEMİZEL E. M. , YILMAZ Z. , ÖZARDA Y.

KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI, vol.22, no.5, pp.679-683, 2016 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 5
  • Publication Date: 2016
  • Doi Number: 10.9775/kvfd.2016.15103
  • Title of Journal : KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI
  • Page Numbers: pp.679-683
  • Keywords: Iron, Binding Capacity, Unsaturated, Erythrocyte Indices, Sheep, DEFICIENCY ANEMIA, PERIPARTAL PERIOD, BINDING-CAPACITY, DAIRY-COWS, MINERALS, BLOOD, TRANSFERRIN, HEMOGLOBIN, PARAMETERS, PROFILES

Abstract

Erythrocyte indices, total iron binding capacity (TIBC) and unsaturated iron binding capacity (UIBC) values provide important information for the diagnosis of anaemia in iron deficiency conditions and inflammatory diseases. The aim of this study was to evaluate the serum iron status and its relation with haematological indexes before and after parturition in sheep. Blood samples were collected from pregnant (n=30) and non-pregnant aged-matching Ivesi sheep (n=30), housed under the same conditions, at 1 week (wk) (+/- 2 days) before expected parturition, in parturition (baseline), at day 1 and at 1, 2, 3, 4, 6, 8 and 12th wk subsequent to the parturition, to determine the serum levels of iron (SI), TIBC and UIBC as well as the haematological parameters. Erythrocyte (RBC) count, haematocrit (Hct) and haemoglobin (Hb) values dropped at 12 wk (P<0.05) according to 1 wk (+/- 2 days) before expected parturition and during parturition. Mean corpuscular volume concentrations were also found lower (P<0.05) at 4-12 wk after parturition, in comparison with their baselines. After the parturition, SI concentration decreased at day 1 (P<0.05) and then remained low (P<0.05) during the study. TIBC was higher for the first 2 wk, but was lower at 6-12 wk compared with its baseline (P<0.05). UIBC values were in parallel to TIBC values after the parturition. In conclusion; negative effects on leukocytes of metabolic stress after delivery should be taken into consideration, as it can trigger the potential problems during this period. In postpartum period, SI levels along with erythrocyte indices can be useful parameters to follow the iron loss by fetus and colostrum. Incompatible results of TIBC and UIBC levels with SI and erythrocyte indices in this study showed that TIBC and UIBC may not be useful biomarkers to evaluate serum iron values, particularly in postpartum period.