Effect of low-dose methyl prednisolone on serum cytokine levels following extracorporeal circulation

Yilmaz M., Ener S., Akalin H., Sagdic K., Serdar O., Cengiz M.

PERFUSION-UK, cilt.14, sa.3, ss.201-206, 1999 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 3
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1177/026765919901400308
  • Dergi Adı: PERFUSION-UK
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.201-206
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

The systemic inflammatory response to cardiopulmonary bypass (CPB) is associated with increased production of cytokines. This systemic inflammatory response characterized by the activation of interleukin-6 (IL-6) and interleukin-8 (IL-8) during and after CPB is well documented. A prospective, randomized, double-blind study was performed so as to understand the effects of low-dose methyl prednisolone sodium succinate (MPSS) on the circulating levels of serum cytokines and clinical outcome.