Malignant glomus tumor with oncocytic features: an unusual presentation of dysphagia

UĞRAŞ N., YERCİ Ö., YALÇINKAYA Ü., Gulcu B., Ozturk E., Yildirim C., ...More

APMIS, vol.123, no.7, pp.613-617, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 123 Issue: 7
  • Publication Date: 2015
  • Doi Number: 10.1111/apm.12394
  • Journal Name: APMIS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.613-617
  • Keywords: Glomus tumor, esophagus, oncocytic, ESOPHAGUS
  • Bursa Uludag University Affiliated: Yes


Glomus tumors in the gastrointestinal tract are unusual, as the previous series in the literature have been mainly limited to the stomach. Less than 10 cases of esophageal glomus tumors have been described in the literature. Oncocytic glomus tumors are a recently identified, rare variant of the glomus tumor. We report a 47-year-old female who presented with an approximately 3-month history of dysphagia and weight loss. Upper gastrointestinal endoscopy showed a black-purple, hypervascular, protruding lesion measuring approximately 65mm at the 37th cm of the esophagus. The patient underwent an Ivor Lewis operation via open thoracotomy. The resected specimen had a protuberant, ulcerated mass measuring 80x35mm in the posterior wall of the esophagus. Based on the histopathological, immunohistochemical and electron microscope findings, the final diagnosis was a malignant glomus tumor with oncocytic features. To our knowledge, this is the first report of a malignant glomus tumor with oncocytic features in an esophageal location.