Is there any association between mycosis fungoides and T-h-1,T-h-2 cytokines and transforming growth factor-beta 1 gene polymorphisms?


YAZİCİ S. , AYDOĞAN K. , SARICAOĞLU H. , BÜLBÜL BAŞKAN E. , Tunali S.

TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY, vol.52, no.4, pp.137-141, 2018 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 52 Issue: 4
  • Publication Date: 2018
  • Doi Number: 10.4274/turkderm.30643
  • Title of Journal : TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY
  • Page Numbers: pp.137-141

Abstract

Background and Design: Cytokines are considered to play a crucial role in the development of mycosis fungoides (MF). Cytokine production is under genetic control and allelic variations of cytokine genes are associated with lower or higher production of cytokines. The aim of this study was to determine any possible cytokine gene polymorphisms that may be a risk factor for the development or progression of MF.