The correlates of benefit from neoadjuvant chemotherapy before surgery in non-small-cell lung cancer: a metaregression analysis


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Bozcuk H., Abalı H., Çoşkun Ş., Aydıner A., Çinkaya A., Demirkazık A., ...More

WORLD JOURNAL OF SURGICAL ONCOLOGY, vol.10, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 10
  • Publication Date: 2012
  • Doi Number: 10.1186/1477-7819-10-161
  • Journal Name: WORLD JOURNAL OF SURGICAL ONCOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Meta-analysis, Metaregression, Mortality, Neoadjuvant chemotherapy, Non-small-cell lung cancer, COMPARING PERIOPERATIVE CHEMOTHERAPY, INDUCTION CHEMOTHERAPY, PLUS SURGERY, METAANALYSIS, GEMCITABINE, CARCINOMA
  • Bursa Uludag University Affiliated: Yes

Abstract

Background: Although neoadjuvant chemotherapy (NCT) is widely used, it is not clear which subgroup of locally advanced non-small-cell lung cancer (NSCLC) patients should be treated with this approach, and if a particular benefit associated with NCT exists. In this study, we aimed to investigate the potential correlates of benefit from NCT in patients with NSCLC.