Influence of erythropoietin therapy on serum prohepcidin levels in dialysis patients

Arabul M., GÜLLÜLÜ M., Yilmaz Y., Eren M. A., Baran B., Gul C. B., ...More

MEDICAL SCIENCE MONITOR, vol.15, no.11, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 11
  • Publication Date: 2009
  • Journal Name: MEDICAL SCIENCE MONITOR
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Bursa Uludag University Affiliated: Yes

Abstract

Background: Anemia is a common finding in dialysis patients. Recent evidence has accrued that hepcidin, an iron regulatory peptide, may play a crucial role in the pathophysiology of this condition. This study investigated the effect of erythropoietin (EPO) therapy on serum levels of prohepcidin, the prohormone of hepcidin, in patients with end-stage renal disease (ESRD) undergoing chronic dialysis treatment.