MEDICAL SCIENCE MONITOR, cilt.15, sa.11, 2009 (SCI-Expanded)
Background: Anemia is a common finding in dialysis patients. Recent evidence has accrued that hepcidin, an iron regulatory peptide, may play a crucial role in the pathophysiology of this condition. This study investigated the effect of erythropoietin (EPO) therapy on serum levels of prohepcidin, the prohormone of hepcidin, in patients with end-stage renal disease (ESRD) undergoing chronic dialysis treatment.