Can BDNF and IL-2 be indicators for the diagnosis in schizophrenic patients with depressive symptoms?

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EKER S. S., Yavasci E. O., CANGÜR Ş., KIRLI S., Sarandol E.

ACTA NEUROPSYCHIATRICA, vol.26, no.5, pp.291-297, 2014 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 26 Issue: 5
• Publication Date: 2014
• Doi Number: 10.1017/neu.2014.13
• Journal Name: ACTA NEUROPSYCHIATRICA
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.291-297
• Keywords: comorbidity, depression, psychoneuroimmunology, schizophrenia, NEUROTROPHIC FACTOR LEVELS, INFLAMMATORY RESPONSE SYSTEM, FACTOR SERUM CONCENTRATIONS, MAJOR DEPRESSION, INTERLEUKIN-2 PRODUCTION, ATYPICAL ANTIPSYCHOTICS, SOLUBLE INTERLEUKIN-2, BIPOLAR DISORDER, CSF LEVELS, BRAIN
• Bursa Uludag University Affiliated: Yes

Abstract

Objective: The aim of the current study is to determine whether serum levels of brain-derived neurotrophic factor (BDNF) and interleukin-2 (IL-2) can be biological indicators for the diagnosis of schizophrenia in patients with depressive symptoms.